Recently, I have friends who started taking Orlistat for weight loss. This drug is well-known among those who are overweight, whether they have taken it before or not. But how effective is it for weight loss? Are there significant side effects? Can it be taken without a doctor's diagnosis?

Orlistat is a relatively safe weight loss medication, approved and recognized by the FDA. The reason for its safety is that under normal circumstances, it is not absorbed into the bloodstream and only works in the intestines, which is why Orlistat is available both over-the-counter and by prescription.

1. Weight loss principle.

   Orlistat is an intestinal fat enzyme inhibitor. As the name suggests, fat enzymes are used to digest and break down fats. Orlistat inhibits these enzymes, thereby directly inhibiting the body's digestion and absorption of fat from the diet. A considerable amount of fat is then excreted through the feces.

   The principle of energy balance for weight loss is understood by most people. That is, when the body's energy expenditure exceeds intake, the body's fat gradually decreases, thus achieving weight loss.

2. Weight loss effect.

   Orlistat can effectively prevent the absorption of oils and fats, with a prevention rate of up to 30% to 50%. Therefore, the effect is quite noticeable, similar to the idea of "eating without absorbing" or "grease passing through the intestines."

   In summary, Orlistat can inhibit intestinal fat absorption, thereby achieving weight loss and slimming effects. However, like any medication, it has side effects. If there are liver or kidney diseases, it is generally not recommended to take Orlistat for weight loss, as it could increase the burden on the liver and kidneys and affect personal health. The editor reminds you to take weight loss medication strictly according to doctor's instructions.